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In vivo analgesic, antipyretic, and anti-inflammatory potential in Swiss albino mice and in vitro thrombolytic activity of hydroalcoholic extract from Litsea glutinosaleaves Biol. Res.
Bhowmick,Rumpa; Sarwa,Md Shahid; Dewan,Syed Masudur Rahman; Das,Abhijit; Das,Binayok; Uddin,Mir Muhammad Nasir; Islam,Md Siddiqul; Islam,Mohammad Safiqul.
BACKGROUND: The study was conducted to evaluate the in vitro thrombolytic activity, and in vivo analgesic, anti-inflammatory and antipyretic potentials of different hydrocarbon soluble extracts of Litsea glutinosaleaves for the first time widely used in the folkloric treatments in Bangladesh. This work aimed to create new insights on the fundamental mechanisms of the plant extracts involved in these activities. RESULTS: In thrombolytic activity assay, a significant clot disruption was observed at dose of 1 mg/mL for each of the extracts (volume 100 μL) when compared to the standard drug streptokinase. The n-hexane, ethyl acetate, chloroform, and crude methanolic extracts showed 32.23 ± 0.26, 37.67 ± 1.31,...
Tipo: Journal article Palavras-chave: Acetic acid induced writhing; Analgesic; Anti-inflammatory; Antipyretic; Litsea glutinosa; Thrombolytic.
Ano: 2014 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602014000100050
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